To meet increasing public demand about facial wrinkles and laxity due to aging, various noninvasive skin tightening & lif ting treatment options are utilized including chemical peeling, fractional laser, radiofrequency & high intensity focused ultrasound; however, the ideal treatment option has yet to be identified1,2,3,4. Recently, High Intensity Focused Ultrasound (HIFU) was used as novel treatment for therapeutic and cosmetic purposes5,6. Focused ultrasound is highly convergent and uses different frequencies of acoustic energy than medical ultrasound devices. The high-frequency focused ultrasound beam is allowed to target the subcutaneous tissues such as the superficial musculoaponeurotic system (SMAS) passing harmlessly through the upper layers of skin. This HIFU beam generate instant microthermal lesions where collagen around the focal point will reach over 65°C and be denatured & contract within milliseconds leading to additional de novo collagen synthesis and remodeling7, 9, 10. HIFU has been demonstrated to be safe and effective in numerous clinical trials as a noninvasive aesthetic treatment and has been cleared by the United States Food and Drug Administration (FDA) to noninvasively lift tissues in the eyebrow, neck, and submentum, and improve lines and wrinkles of the décollete10.
In proposed study, ef f icacy evaluation of the Ultraformer III (HIFU) treatment was done on the basis of clinical improvement, adverse effects and patient satisfaction, these parameters were evaluated using clinical photographs and by a Subject Global Aesthetic Improvement Scale (SGAIS) and Physician Global Aesthetic Improvement Scale (PGAIS) scores at 3 months after treatment, in 20 patients older than 25 years of age